chloroacetamide

Org. Synth. , 7, 16

With competitive price and timely delivery, Yufeng sincerely hope to be your supplier and partner.

DOI: 10./orgsyn.007.

CHLOROACETAMIDE

[

Acetamide, α-chloro-

]

Submitted by W. A. Jacobs and M. Heidelberger.

Checked by C. S. Marvel and D. D. Coffman.

1. Procedure

In a

2-l. round-bottomed flask

fitted with a

mechanical stirrer

and surrounded by an

ice-salt bath

is placed

215 g. (1.75 moles) of

ethyl chloroacetate

(Note 1)

. Vigorous stirring is started, and to the cold ester

(Note 2)

200 cc. of chilled aqueous

ammonia

Are you interested in learning more about 105-39-5? Contact us today to secure an expert consultation!

(sp. gr. 0.9) is added. The solution is stirred in the cold for about fifteen minutes; then another

200-cc. portion of aqueous

ammonia

is added, and the stirring is continued for about fifteen minutes. The mixture is then allowed to stand for thirty minutes, filtered with suction, and washed with two

25-cc. portions of cold water to remove

ammonium chloride

. The yield of air-dried material melting at

118&#;119°

(Note 3)

is

128&#;138 g.

(

78&#;84

per cent of the theoretical amount).

This product contains traces of

ammonium chloride

which may be removed by crystallization from water. When

100 g.

of crude product is recrystallized from 400 cc. of water, about

80 g.

of product is obtained. The recrystallized product melts at

119&#;120°

.

The company is the world’s best buy tert butyl acetate supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.

Additional information: This substance is on the Non-domestic Substances List (NDSL).

The manufacture or import of a substance on the NDSL may be subject to notification under the New Substances Notification Regulations (Chemicals and Polymers). Following notification, Environment and Climate Change Canada and Health Canada carry out a joint assessment process to determine whether there is a potential for adverse effects on the environment and human health.

For more information on the regulatory requirements for new chemicals and polymers, refer to the Guidance document for the New Substances Notification Regulations (Chemicals and Polymers).